The American journal of geriatric pharmacotherapy
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Am J Geriatr Pharmacother · Mar 2006
Meta AnalysisEfficacy and tolerability of solifenacin in elderly subjects with overactive bladder syndrome: a pooled analysis.
Overactive bladder (OAB) syndrome is characterized by urinary frequency and urgency with or without urge incontinence, and often accompanied by nocturia. The prevalence of OAB increases with aging; it is a particularly common condition among the elderly, affecting at least 25% of people aged > or = 65 years. ⋯ In these pooled analyses, solifenacin 5 and 10 mg once daily were efficacious and well tolerated in the treatment of these elderly subjects with OAB. Solifenacin therapy was also associated with a high level of persistence in a 40-week extension trial.