Current heart failure reports
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Curr Heart Fail Rep · Jun 2010
Randomized Controlled Trial Multicenter StudyIron in heart failure: friend or foe?
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Curr Heart Fail Rep · Jun 2010
ReviewRelaxin: review of biology and potential role in treating heart failure.
Relaxin is a naturally occurring human peptide initially identified as a reproductive hormone. More recently, relaxin has been shown to play a key role in the maternal hemodynamic and renal adjustments that accommodate pregnancy. ⋯ In addition, the other known biologic properties of relaxin, including anti-inflammatory effects, extracellular matrix remodeling effects, and angiogenic and anti-ischemic effects, all may play a role in potential benefits of relaxin therapy. Ongoing, large-scale clinical testing will provide additional insights into the potential role of relaxin in the treatment of heart failure.