Clinical trials : journal of the Society for Clinical Trials
-
Randomized Controlled Trial
Design of a randomized trial of diabetes genetic risk testing to motivate behavior change: the Genetic Counseling/lifestyle Change (GC/LC) Study for Diabetes Prevention.
The efficacy of diabetes genetic risk testing to motivate behavior change for diabetes prevention is currently unknown. ⋯ We designed a randomized clinical trial designed to explore the motivational impact of disclosing both higher than average and lower than average genetic risk for type 2 diabetes. This design allowed exploration of both increased risk and false reassurance, and has implications for future studies in translational genomics.