Heart rhythm : the official journal of the Heart Rhythm Society
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    Randomized Controlled Trial Multicenter StudyDigoxin in patients with permanent atrial fibrillation: data from the RACE II study.The Atrial Fibrillation Follow-up Investigation of Rhythm Management trial showed that digoxin was associated with increased mortality in patients with atrial fibrillation. ⋯ The use of digoxin was not associated with increased morbidity and mortality. 
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    Randomized Controlled TrialImpact of biatrial defragmentation in patients with paroxysmal atrial fibrillation: results from a randomized prospective study.Single procedure success rates of pulmonary vein isolation (PVI) in patients with paroxysmal atrial fibrillation (PAF) are still unsatisfactory. In patients with persistent atrial fibrillation (AF), ablation of complex fractionated atrial electrograms (CFAEs) after PVI results in improved outcomes. ⋯ Patients with sustained AF after PVI in a PAF cohort are rare. Regarding AF/AT recurrence, these patients did not benefit from further CFAE ablation compared to PVI alone, but are exposed to longer procedure duration, fluoroscopy time, and radiofrequency application time.