Acta neurochirurgica
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Acta neurochirurgica · Jan 2003
Randomized Controlled Trial Comparative Study Clinical TrialProspective comparative study of the effectiveness of epidural morphine and ropivacaine for management of pain after spinal operations.
Evaluation of the effectiveness of local application of morphine or ropivacaine for treatment of local and radicular pain after lumbar disc operations. Critical review of the literature about the possibilities of management of postoperative pain after spinal operations. ⋯ Local application of 5 mg morphine sulfate is effective in prevention or reduction of postoperative lumbar and radicular pain after lumbar disc operations. Ropivacain is less effective. The routine application of epidural morphine at the end of spinal operations can be recommended. It also can be justified to try to prolong the morphine effect by mixing it into a paste as described by Needham and by Hurlbert, and to irrigate the operative field with ropivacaine at the end of the operation.