Kathmandu University medical journal (KUMJ)
-
Kathmandu Univ Med J (KUMJ) · Oct 2012
Randomized Controlled TrialPreemptive use of small dose fentanyl suppresses fentanyl induced cough.
Fentanyl, a synthetic opioid, is a popular choice amongst anaesthesiologists in the operating room. Pre induction intravenous fentanyl bolus is associated with coughing in 28-65% of patients. Fentanyl induced cough is not always benign and can be remarkably troublesome at the most critical moment of anaesthesia when airway reflex is lost. ⋯ Pre-emptive use of minimal dose fentanyl 25 μg administered one minute before a larger bolus dose of fentanyl (125 or 150 μg) can effectively suppress cough.