Kathmandu University medical journal (KUMJ)
-
Kathmandu Univ Med J (KUMJ) · Oct 2011
Randomized Controlled TrialUse of gabapentin, esmolol or their combination to attenuate haemodynamic response to laryngoscopy and intubation.
Laryngoscopy and intubation increases blood pressure and heart rate. ⋯ Combination of gabapentin and esmolol in this study design is safe and better attenuates both the pressor and tachycardic response to laryngoscopy and intubation, than either agent alone.
-
Kathmandu Univ Med J (KUMJ) · Jul 2011
Randomized Controlled Trial Comparative StudyPropofol sedation during spinal anaesthesia- a dose finding study.
It is important to be able to measure and maintain a specific sedation level to compare outcomes of different levels of sedation during anesthesia and the aims include general patient comfort, freedom from specific discomfort, and some amnesia for both the block procedure and the surgical operation, in order to meet the patient preference and safety. In this prospective randomized clinical study, we compared the three different infusion doses of propofol. ⋯ Propofol infusion at the rate of 50 mcg/kg/min for sedation in spinal anaesthesia provides optimal sedation, early awakening and excellent satisfaction level in the postoperative period.
-
Kathmandu Univ Med J (KUMJ) · Jan 2011
Randomized Controlled TrialRectal misoprostol versus intramuscular oxytocin for prevention of post partum hemorrhage.
Postpartum hemorrhage (PPH) is an important cause of maternal morbidity and mortality especially in the developing countries.,Compared to expectant management, active management decreases the incidence of PPH. ⋯ Rectal misoprostol is as effective as intravenous oxytocin in preventing postpartum hemorrhage with the similar incidence of side effects and is worthwhile to be used as a uterotonic agent for the routine management of third stage of labor.
-
Kathmandu Univ Med J (KUMJ) · Jan 2011
Randomized Controlled TrialComparison of sniffing position and simple head extension for visualization of glottis during direct laryngoscopy.
The ability of good glottis visualization during direct laryngoscopy is major determinant of easy tracheal intubation. Sniffing position for laryngoscopy is considered as gold standard and ideal position. Several studies have questioned the validation of sniffing potion. ⋯ Glottic visualization and intubation difficulty score was better in sniffing position as compared to simple head extension.
-
Kathmandu Univ Med J (KUMJ) · Apr 2010
Randomized Controlled TrialEffect of preloading on hemodynamic of the patient undergoing surgery under spinal anaesthesia.
Hypotension and bradycardia after conduction of spinal anaesthesia are common side effects because of sympathetic blockade. Efforts to prevent these complications have been attempted like preloading with crystalloids, colloids or use of vasopressors. The role of volume preloading to prevent hemodynamic changes associated with spinal anaesthesia has been recently questioned. ⋯ On the basis of findings, it is concluded that volume preloading had no effect on the incidence of hypotension and bradycardia after spinal anaesthesia.