Kathmandu University medical journal (KUMJ)
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Kathmandu Univ Med J (KUMJ) · Jan 2009
Randomized Controlled TrialIntraperitoneal and periportal injection of bupivacaine for pain after laparoscopic cholecystectomy.
To study the analgesic efficacy of intraperitoneal and periportal injection of bupivacaine following laparoscopic cholecystectomy. ⋯ Intraperitoneal and periportal injection of bupivacaine is effective in decreasing pain after laparoscopic cholecystectomy.
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Kathmandu Univ Med J (KUMJ) · Jul 2008
Randomized Controlled Trial Comparative StudyEffectiveness of addition of neostigmine or dexamethasone to local anaesthetic in providing perioperative analgesia for brachial plexus block: A prospective, randomized, double blinded, controlled study.
Various local anaesthetic agents are used for brachial plexus block.We compared effectiveness of addition of Dexamethasone versus Neostigmine to Lignocaine, adrenaline admixtures for Brachial plexus block in providing perioperative analgesia. ⋯ The onsets of action, duration of analgesia were better in dexamethasone group and also need less number of rescue analgesics requirement.
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Kathmandu Univ Med J (KUMJ) · Jul 2008
Randomized Controlled Trial Comparative StudyAntiemetic prophylaxis against postoperative nausea and vomiting with ondansetron-dexamethasone combination compared to ondansetron or dexamethasone alone for patients undergoing laparoscopic cholecystectomy.
Postoperative nausea and vomiting (PONV) is a common distressing experience in patients following laparoscopic surgeries. This study was aimed at comparing the efficacies of Ondansetron-Dexamethasone combination with each drug alone as a prophylaxis against PONV in patients after elective laparoscopic cholecystectomy done under general anaesthesia. ⋯ Combination of Ondansetron and Dexamethasone is better than each drug alone in preventing PONV after laparoscopic cholecystectomy. Dexamethasone alone is significantly less effective in preventing early vomiting compared to its combination with Ondansetron; whereas Ondansetron alone is less effective against late PONV as compared with combination therapy.
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Kathmandu Univ Med J (KUMJ) · Apr 2008
Randomized Controlled Trial Comparative StudyMidazolam for caudal analgesia in children: comparison with caudal bupivacaine.
Caudal analgesia is the most popular and commonly used regional anaesthesia technique for post operative analgesia in children undergoing lower limb, anoperineal and abdominal surgical procedures. It is commonly applied in all the paediatric patients undergoing the above mentioned surgery, as the goal of balanced anaesthesia is not only limited to intraoperative period but also good analgesia in post operative period. Many drugs like morphine, Pethidine, Neostigmine etc have been used as analgesic agent via the caudal route but not without their side effects. So Midazolam was used as an alternative drug as it may not be associated with the side effects encountered with the other drugs. ⋯ We conclude that caudal Midazolam in a dose of 50 microg/kg provides equivalent analgesia to Bupivacaine 0.25%, when administered in a volume of 1 ml/kg for children undergoing unilateral inguinal herniotomy for hernia or high ligation of processus vaginalis for hydrocoele.
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Kathmandu Univ Med J (KUMJ) · Oct 2007
Randomized Controlled TrialOral administration of intravenous solution of midazolam mixed in syrup of paracetamol is an effective way of premedicating children undergoing surgery under general anaesthesia.
The purpose of this study was to evaluate the efficacy of injection midazolam administered by oral route mixed in paracetamol syrup as a premedication in children undergoing surgery. ⋯ It was concluded that injection midazolam mixed in syrup paracetamol administered orally is a convenient and efficient method of premedicating children undergoing general anaesthesia. Parent-child separation and induction of anaesthesia was smooth and the recovery uneventful in children premedicated with oral midazolam.