Clinical toxicology : the official journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists
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Clin Toxicol (Phila) · Jun 2007
Case ReportsSuccessful organ transplantation after treatment of fatal cyanide poisoning with hydroxocobalamin.
Cyanide-poisoned patients are potential organ donors provided that organs are not damaged by the poison or by antidotal treatment. ⋯ Anoxic cardiac arrest following acute cyanide poisoning treated with hydroxocobalamin (5 g + 5 g) was not a contraindication to organ transplantation after confirmed encephalic death in this patient.
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Clin Toxicol (Phila) · Jun 2007
Case ReportsUrinary serotonin level is associated with serotonin syndrome after moclobemide, sertraline, and citalopram overdose.
Altered mental status, autonomic dysfunction, and neuromuscular abnormalities are a characteristic triad of serotonin syndrome. No laboratory tests confirm the diagnosis of serotonin syndrome. ⋯ The urinary serotonin level is increased in serotonin syndrome due to a monoamine oxidase inhibitor and selective serotonin-reuptake inhibitors overdose. It is possible that urinary serotonin concentration could be used as a biochemical marker of serotonin syndrome.
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Clin Toxicol (Phila) · Jun 2007
Human poisoning in Thailand: The Ramathibodi Poison Center's experience (2001-2004).
To identify poisoning and toxic exposure pattern, severity, and clinical outcome in Thailand during 2001 to 2004. ⋯ Features of poisoning in Thailand were different from those in Western countries. Pesticide poisoning was the major problem in Thailand. Intentional suicide was the major circumstance of poison exposure in adults, but accidental exposure was the major reason of exposure in children.
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Clin Toxicol (Phila) · Jun 2007
Case ReportsReversal of salicylate-induced euglycemic delirium with dextrose.
Salicylate poisoning inhibits Krebs cycle enzymes and uncouples oxidative phosphorylation. Under these circumstances, we hypothesize that CNS glucose supply is sometimes unable to keep up with demand resulting in hypoglycorrhacia and delirium even in the face of serum euglycemia. Supporting this conjecture, we report two euglycemic patients with salicylate-induced delirium who responded to boluses of concentrated dextrose with a prompt improvement in mental status.