Clinics
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This experimental study focused on the intra- and inter-rater reproducibility of vertical bone level (VBL) measurements at strategic mini-implants (MI) using digital panoramic radiographs (PR). ⋯ DRKS00007589, www.germanctr.de.
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This study aimed to develop and internally validate a prediction model for estimating the risk of spontaneous abortion in early pregnancy. ⋯ The prediction model demonstrated good performance in estimating spontaneous abortion risk in early pregnancy based on demographic, clinical, and psychosocial factors. Further external validation is recommended before clinical application.
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circCPA4 has been defined to be an oncogenic gene. This study examined whether circCPA4 regulates Prostate Cancer (PC) development and revealed its molecular mechanism. ⋯ circCAP4 acts as a novel oncogenic factor in PC, accelerating the malignant behavior of PC cells via miR-491-5p/SHOC2 interaction. This novel ceRNA axis may be a potential target for PC drug development and targeted therapy in the future.
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Review Meta Analysis
Pharmacological treatment for obstructive sleep apnea: A systematic review and meta-analysis.
Summarize the evidence on drug therapies for obstructive sleep apnea. ⋯ CRD42022362639.
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Review Meta Analysis
Gastric adenocarcinoma and periodontal disease: A systematic review and meta-analysis.
The oral cavity is a link between of external environment with gastrointestinal tract. Studies are controversial on the presence of Periodontal Disease (PD) and its association with Gastric Adenocarcinoma (GAC). ⋯ The presence of PD the risk of GAC suggesting that its infectious-inflammatory process of PD may be related to GAC development. Further investigations on the oral-gastric microbiota and its role in the carcinogenesis of gastric cancer should be carried out, and the screening of patients with potential risk for GAC should be considered in the clinical practice of dentists.