Clinics
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Randomized Controlled Trial
Structured respiratory physiotherapy protocol for resolution of atelectasis in pediatric intensive care.
Children are at higher risk of atelectasis due to their anatomical and physiological particularities. Several physiotherapy techniques are used to treat atelectasis, but only four studies cite methods in pediatric patients undergoing Invasive Mechanical Ventilation (IMV). The objective of this study was to evaluate the Structured Respiratory Physiotherapy Protocol (SRPP) for airway clearance and lung reexpansion for infants on IMV with atelectasis. ⋯ There were large within-group effects on the reduction of WD in the CG after intervention in both the CG (Hedges' g = -1.53) and IG (Hedges' g = -2.2). There was a moderate effect on LUS reduction in the CG (Hedges' g = -0.64) and a large effect on IG (Hedges' g = -1.88). This study has shown that the SRPP appears to be safe and may be effective in improving airway clearance and lung reexpansion in children on IMV with atelectasis.
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Randomized Controlled Trial
Effect of Specific mode electroacupuncture stimulation combined with NGF during the ischaemic stroke: Study protocol for a randomized controlled trial.
The emergence of the Nerve Growth Factor (NGF) has promoted the development of neuroprotective therapy; however, it has little effect on cerebral ischemia because of its poor Blood-Brain Barrier (BBB) permeability. Specific Mode Electroacupuncture Stimulation (SMES) can open BBB safely and effectively; however, it has shown inconclusive clinical effects and indirect clinical evidence in the recovery phase. Hence, the authors conducted a multicentre, randomized, placebo-controlled, assessor-blinded clinical trial to assess the effectiveness and safety of SMES combined with NGF treatment used during ischaemic stroke recovery. ⋯ This study will provide clinical evidence for the efficacy and safety of SMES combined with NGF in the treatment of stroke patients.
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Randomized Controlled Trial
Microablative fractional radiofrequency for sexual dysfunction and vaginal Trophism: A randomized clinical trial.
To evaluate Microablative Fractional Radiofrequency (MAFRF) as a possible option in treating vaginal atrophy. ⋯ Radiofrequency was comparable in efficacy to estrogen administration for treating vulvovaginal atrophy. It deserves consideration as a viable option in managing this condition.
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Randomized Controlled Trial
Prediction of intensive care admission and hospital mortality in COVID-19 patients using demographics and baseline laboratory data.
Optimized allocation of medical resources to patients with COVID-19 has been a critical concern since the onset of the pandemic. ⋯ The authors developed and validated prognostic scores that use readily available clinical and laboratory information to predict ICU admission and mortality in COVID-19. These scores can become valuable tools to support clinical decisions and improve the allocation of limited health resources.
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Randomized Controlled Trial
Stroke in children and adolescents: Analysis of electrophysiological and behavioral assessment findings of auditory processing.
This study aimed to analyze the auditory processing behavior of children and adolescents diagnosed with stroke and compare it with that of typically developing individuals. ⋯ This study showed that children and adolescents with stroke performed worse in electrophysiological and behavioral tests of auditory processing assessed using the auditory evoked potentials. These data reinforce the hypothesis that stroke-related lesions compromise the neural mechanisms underlying auditory processing.