Clinics
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Review Meta Analysis
Melatonin improves fertilization rate in assisted reproduction: Systematic review and meta-analysis.
Melatonin is a hormone produced by the pineal gland and it has antioxidant properties. ⋯ Melatonin had beneficial effects such as the improvement in the fertilization rate, although the authors did not obtain significance in the clinical pregnancy rate.
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Visceral Crisis (VC) in breast cancer is a critical scenario when the burden of metastatic disease results in rapid deterioration of organ functions. There are no widely accepted objective clinical criteria for the definition of VC, and different studies have reported diverse clinical conditions such as visceral crises. Diagnosis of VC is associated with a dismal prognosis and the management of this condition is currently based on limited retrospective evidence and expert opinions. ⋯ Nevertheless, in the case of hormone receptor-positive breast cancer, the role of chemotherapy as the treatment of choice for VC has been recently questioned, since endocrine therapy plus CDK4/6 inhibitors yielded similar response rates, with better quality of life. For HER2-positive and triple-negative breast cancer, combined chemotherapy (plus HER2-directed therapy for HER2-positive) remains a standard option for VC, but novel effective drugs such as antibody-drug conjugates are emerging and their role in the VC context shall soon be elucidated. This review aims to critically discuss the definition, prognosis, management, and future directions regarding the visceral crisis in metastatic breast cancer.
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Review Meta Analysis
The effects of art therapy interventions on anxiety in children and adolescents: A meta-analysis.
This study aimed to assess the effects of art therapy on anxiety among children and adolescents. ⋯ Art therapy significantly improved the anxiety symptoms of children and adolescents, positioning it as an effective means of treating anxiety.
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Review Meta Analysis
The effects of art therapy interventions on anxiety in children and adolescents: A meta-analysis.
This study aimed to assess the effects of art therapy on anxiety among children and adolescents. ⋯ Art therapy significantly improved the anxiety symptoms of children and adolescents, positioning it as an effective means of treating anxiety.
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Review Meta Analysis
Low-level red-light therapy for myopia control in children: A systematic review and meta-analysis.
Low-Level Red-Light (LLRL) Therapy is a safe and natural way to promote healing and reduce inflammation in the body. When it comes to treating myopia in children, LLRL therapy is recent, and its efficacy and safety still are not clear. ⋯ LLRL therapy is a non-invasive, effective, and safe short-term treatment option; however, long-term evaluation, particularly in comparison to other therapies, requires additional investigation.