Journal of cancer research and therapeutics
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The relationship between methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphisms and lung cancer susceptibility is controversial according to the case-control or cohort study. We perform this meta-analysis to evaluate the association between MTHFR 677C>T polymorphisms and lung cancer risk based on Chinese Han population. ⋯ Chinese Han people with TT/CT genotype of MTHFR gene may have increased the risk of developing breast cancer.