International journal of obesity : journal of the International Association for the Study of Obesity
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Randomized Controlled Trial
Meal size can be decreased in obese subjects through pharmacological acceleration of gastric emptying (The OBERYTH trial).
Entry of nutrients into the small intestine activates neuro-hormonal signals that regulate food intake through induction of satiation. ⋯ Meal size can be reduced in overweight/obese subjects by pharmacologically accelerating GE. This may be a reasonable target in obesity management.
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To investigate the relationship between body mass index (BMI), waist circumference (WC) or waist-hip ratio (WHR) and all-cause mortality or cause-specific mortality. ⋯ It might be prudent not to use BMI as the sole measure to summarize body size. The alternatives WC and WHR may more clearly define the health risks associated with excess body fat accumulation. The lack of association between elevated BMI and mortality may reflect the secular decline in CVD mortality.