Journal of hospital medicine : an official publication of the Society of Hospital Medicine
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Review Meta Analysis
Procalcitonin-guided antibiotic therapy: a systematic review and meta-analysis.
The utility of procalcitonin to manage patients with infections is unclear. A systematic review of comparative studies using procalcitonin-guided antibiotic therapy in patients with infections was performed. ⋯ Procalcitonin guidance can safely reduce antibiotic usage when used to discontinue antibiotic therapy in adult ICU patients and when used to initiate or discontinue antibiotics in adult patients with respiratory tract infections.