Vascular health and risk management
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Vasc Health Risk Manag · Jan 2013
Randomized Controlled TrialEffects of CPAP on "vascular" risk factors in patients with obstructive sleep apnea and arterial hypertension.
The aim of this study was to assess the effects of continuous positive airway pressure (CPAP) on arterial stiffness, central blood pressure, and reflected pulse wave characteristics in patients with severe obstructive sleep apnea (OSA) and stage 2-3 arterial hypertension. ⋯ Effective CPAP for 3 weeks resulted in a significant additional decrease in office BP, ambulatory BP monitoring, central BP, and augmentation index, together with an improvement in arterial stiffness parameters, ie, cfPWV and AASI, in a group of hypertensive patients with OSA.