Computational and mathematical methods in medicine
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Comput Math Methods Med · Dec 2010
Modelling of peripheral fluid accumulation after a crystalloid bolus in female volunteers - a mathematical study.
To simultaneously model plasma dilution and urinary output in female volunteers. ⋯ The experimental results showed a large variability in spite of a homogenous volunteer group. It was possible to compute the infusion amount, plasma dilution and simultaneous urinary output for each consecutive time point and thereby the empirical peripheral fluid accumulation. The variability between individuals may be explained by differences in tissue and hormonal responses to fluid boluses, which needs to be further explored.