The clinical respiratory journal
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Review Meta Analysis
Efficacy of intrapleural instillation of fibrinolytics for treating pleural empyema and parapneumonic effusion: a meta-analysis of randomized control trials.
The effects of intrapleural fibrinolysis for treating pleural empyema and parapneumonic effusion remain uncertain. ⋯ The present results show that intrapleural fibrinolysis with urokinase may be potentially effective for reducing the need for surgery. Intrapleural fibrinolytic therapy is effective for shortening the lengths of hospital stays without increasing the incidence of severe side effects.