The American journal of cardiology
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of propafenone versus procainamide for the acute treatment of atrial fibrillation after cardiac surgery.
A prospective, randomized, double-blind study to compare the efficacy in terminating postoperative atrial fibrillation of the class Ic drug propafenone versus class Ia drug procainamide was conducted. Intravenous propafenone was superior to procainamide in achieving rapid cardioversion and a better rate control with a lower incidence of symptomatic hypotension.