Journal of neurosurgery. Pediatrics
-
J Neurosurg Pediatr · Jul 2019
Posterior fossa syndrome and increased mean diffusivity in the olivary bodies.
Posterior fossa syndrome (PFS) is a common postoperative complication following resection of posterior fossa tumors in children. It typically presents 1 to 2 days after surgery with mutism, ataxia, emotional lability, and other behavioral symptoms. Recent structural MRI studies have found an association between PFS and hypertrophic olivary degeneration, which is detectable as T2 hyperintensity in the inferior olivary nuclei (IONs) months after surgery. In this study, the authors investigated whether immediate postoperative diffusion tensor imaging (DTI) of the ION can serve as an early imaging marker of PFS. ⋯ Increased MD in the ION is associated with development of PFS. ION MD changes may represent an early imaging marker of PFS.
-
J Neurosurg Pediatr · Jul 2019
Association between postoperative DTI metrics and neurological deficits after posterior fossa tumor resection in children.
Resection of posterior fossa tumors in children may be associated with persistent neurological deficits. It is unclear if these neurological deficits are associated with persistent structural damage to the cerebellar pathways. The purpose of this research was to define longitudinal changes in diffusion tensor imaging (DTI) metrics in white matter cerebellar tracts and the clinical correlates of these metrics in children undergoing resection of posterior fossa tumors. ⋯ DTI after resection of posterior fossa tumors in children shows that persistent reduction of SCP FA is associated with ataxia at follow-up.