Archives of cardiovascular diseases
-
Arch Cardiovasc Dis · Oct 2013
Review Meta AnalysisCytochrome CYP2C19 polymorphism and risk of adverse clinical events in clopidogrel-treated patients: a meta-analysis based on 23,035 subjects.
Previous studies have investigated the relationship between CYP2C19 polymorphism and clinical prognosis in coronary artery disease patients treated with clopidogrel, but the results were inconsistent. ⋯ CYP2C19 polymorphism is significantly associated with risk of adverse clinical events in clopidogrel-treated patients.
-
Arch Cardiovasc Dis · Oct 2013
Ultrasound-based teaching of cardiac anatomy and physiology to undergraduate medical students.
Ultrasonography is a non-invasive imaging modality that offers the opportunity to teach living cardiac anatomy and physiology. ⋯ Cardiac anatomy and physiology teaching using ultrasound is feasible for undergraduate medical students and enhances their motivation to improve their knowledge. Student and teacher feedback on the course was very positive.
-
Arch Cardiovasc Dis · Oct 2013
Multicenter Study Comparative StudyPersistent atrial fibrillation presenting in sinus rhythm: pulmonary vein isolation versus pulmonary vein isolation plus electrogram-guided ablation.
The classification of atrial fibrillation as paroxysmal or persistent (PsAF) is clinically useful, but does not accurately reflect the underlying pathophysiology and is therefore a suboptimal guide to selection of ablation strategy. ⋯ The addition of EGM-guided ablation requires fewer procedures to achieve similar clinical efficacy in mid-term follow-up compared with a PVI-only strategy in patients with PsAF presenting for ablation in SR.
-
Arch Cardiovasc Dis · Oct 2013
Multicenter StudyEvaluation of the impact of the recent controversy over statins in France: the EVANS study.
The effect of statins on the prevention of cardiovascular events is well-established. However, a recent controversy in France questioned the value of statins, especially in primary prevention. ⋯ Recent controversy over statins could induce a large proportion of patients to stop their medication and generate a large number of major cardiovascular events.