JACC. Cardiovascular interventions
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JACC Cardiovasc Interv · Dec 2013
Review Meta AnalysisDevice closure of patent foramen ovale versus medical therapy in cryptogenic stroke: a systematic review and meta-analysis.
This study sought to perform a meta-analysis of randomized controlled trials comparing device closure with medical therapy in the prevention of recurrent neurological events in patients with cryptogenic stroke and patent foramen ovale. ⋯ Our meta-analysis suggests that PFO closure is beneficial as compared to medical therapy in the prevention of recurrent neurological events. This meta-analysis helps to further strengthen the role of device closure in cryptogenic stroke.
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JACC Cardiovasc Interv · Dec 2013
Review Meta AnalysisLeft main coronary artery stenosis: a meta-analysis of drug-eluting stents versus coronary artery bypass grafting.
The goal of this study was to provide a systematic review comparing the long-term outcomes of percutaneous coronary intervention (PCI) with drug-eluting stents (DES) versus coronary artery bypass graft surgery (CABG) for unprotected left main coronary artery (UPLM) stenosis. ⋯ Our findings suggest that PCI with DES is a safe and durable alternative to CABG for the revascularization of UPLM stenosis in select patients at long-term follow-up.