JACC. Cardiovascular interventions
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JACC Cardiovasc Interv · Feb 2015
Randomized Controlled Trial Multicenter StudyReal-time ultrasound guidance facilitates transradial access: RAUST (Radial Artery access with Ultrasound Trial).
This study sought to assess the utility of ultrasound (US) guidance for transradial arterial access. ⋯ Ultrasound guidance improves the success and efficiency of radial artery cannulation in patients presenting for transradial catheterization. (Radial Artery Access With Ultrasound Trial [RAUST]; NCT01605292).
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JACC Cardiovasc Interv · Feb 2015
Multicenter Study Clinical TrialHealth status after transcatheter aortic valve replacement in patients at extreme surgical risk: results from the CoreValve U.S. trial.
The purpose of this study was to characterize health status outcomes after transcatheter aortic valve replacement (TAVR) with a self-expanding bioprosthesis among patients at extreme surgical risk and to identify pre-procedural patient characteristics associated with a poor outcome. ⋯ Among patients with severe aortic stenosis, TAVR with a self-expanding bioprosthesis resulted in substantial improvements in both disease-specific and generic health-related quality of life, but there remained a large minority of patients who died or had very poor quality of life despite TAVR. Predictive models based on a combination of clinical factors as well as disability and frailty may provide insight into the optimal patient population for whom TAVR is beneficial. (Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in High Risk and Very High Risk Subjects Who Need Aortic Valve Replacement; NCT01240902).