Circulation. Arrhythmia and electrophysiology
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Circ Arrhythm Electrophysiol · Aug 2014
Randomized Controlled Trial Multicenter StudyPR interval identifies clinical response in patients with non-left bundle branch block: a Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy substudy.
In Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy (MADIT-CRT), patients with non-left bundle branch block (LBBB; including right bundle branch block, intraventricular conduction delay) did not have clinical benefit from cardiac resynchronization therapy with defibrillator (CRT-D). We hypothesized that baseline PR interval modulates clinical response to CRT-D therapy in patients with non-LBBB. ⋯ http://clinicaltrials.gov; Unique Identifier: NCT00180271.