Journal of bronchology & interventional pulmonology
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J Bronchology Interv Pulmonol · Oct 2014
Randomized Controlled Trial Multicenter StudyThe IBV Valve trial: a multicenter, randomized, double-blind trial of endobronchial therapy for severe emphysema.
Lung volume reduction surgery improves quality of life, exercise capacity, and survival in selected patients but is accompanied by significant morbidity. Bronchoscopic approaches may provide similar benefits with less morbidity. ⋯ This trial had technical and statistical success but partial-bilateral endobronchial valve occlusion did not obtain clinically meaningful results. Safety results were acceptable and compare favorably to lung volume reduction surgery and other bronchial valve studies. Further studies need to focus on improved patient selection and a different treatment algorithm.
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J Bronchology Interv Pulmonol · Apr 2012
Multicenter Study Comparative StudyA comparison of the diagnostic yield of rigid and semirigid thoracoscopes.
Medical thoracoscopy has an important place in the diagnosis and management of pleural disease. However, the application of this procedure is limited in the United Kingdom. This may be partly because respiratory physicians remain unfamiliar with standard rigid thoracoscopy instruments. ⋯ Statistically, this difference was not significant (95% confidence intervals, -0.11 to 0.17). Our study demonstrates that the semirigid thoracoscope achieves a diagnostic yield similar to that of the conventional rigid instrument despite the smaller biopsy size. Both instruments remain valuable in the evaluation and management of pleural disease.