Journal of hepato-biliary-pancreatic sciences
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J Hepatobiliary Pancreat Sci · Aug 2018
Multicenter StudyPreoperative assessment of frailty predicts age-related events after hepatic resection: a prospective multicenter study.
Age-related events, such as cardiopulmonary complications, delirium, transfer to a rehabilitation facility, and dependency are a major problem after hepatic resection in the elderly. This prospective multicenter study aimed to preoperatively evaluate frailty in the elderly according to a phenotypic frail index, named the "Kihon Checklist (KCL)," to predict "age-related events" after hepatic resection. ⋯ Frailty evaluated by KCL in the elderly can predict postoperative age-related events after hepatic resection.
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J Hepatobiliary Pancreat Sci · Feb 2016
Randomized Controlled Trial Multicenter StudyUse of TachoSil(®) patches to prevent pancreatic leaks after distal pancreatectomy: a prospective, multicenter, randomized controlled study.
We performed a prospective, multicenter, randomized controlled study to investigate the clinical outcomes, including postoperative pancreatic fistulas (POPF), after using the TachoSil® patch in distal pancreatectomy (NCT01550406). ⋯ This study showed that the TachoSil® patch did not reduce the incidence of POPF after distal pancreatectomy.
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J Hepatobiliary Pancreat Sci · Nov 2015
Multicenter Study Clinical TrialFeasibility and efficacy of gemcitabine plus cisplatin combination therapy after curative resection for biliary tract cancer.
The aim of this multi-institutional study was to assess the feasibility and the efficacy of gemcitabine plus cisplatin (CDDP) combination therapy (GC therapy) for biliary tract cancer (BTC) in the adjuvant setting. ⋯ Standard dose of GC therapy is tolerable in patients with BTC who underwent curative resection either with or without major hepatectomy. The survival effect of this regimen is promising, but further comparative study is needed.
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J Hepatobiliary Pancreat Sci · Nov 2015
Randomized Controlled Trial Multicenter StudyEfficacy of preoperative dexamethasone for postoperative nausea and vomiting after laparoscopic cholecystectomy: a large-scale, multicenter, randomized, double-blind, placebo-controlled trial in Japan.
To assess the efficacy of preoperative dexamethasone for postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy (LC) in Japan. ⋯ Routine use of preoperative dexamethasone for PONV after elective LC in Japan was not shown to have a clinical advantage.
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J Hepatobiliary Pancreat Sci · Oct 2015
Multicenter Study Comparative StudyLong-term and perioperative outcomes of laparoscopic versus open liver resection for hepatocellular carcinoma with propensity score matching: a multi-institutional Japanese study.
The aim of this study was to compare the long-term outcomes and perioperative outcomes of laparoscopic liver resection (LLR) with those of open liver resection (OLR) for hepatocellular carcinoma (HCC) between well-matched patient groups. ⋯ Compared with OLR, LLR in selected patients with HCC showed similar long-term outcomes, associated with less blood loss, shorter hospital stay, and fewer postoperative complications.