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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
The spirometric efficacy of once-daily dosing with tiotropium in stable COPD: a 13-week multicenter trial. The US Tiotropium Study Group.
To compare the bronchodilator efficacy and safety of tiotropium and placebo. ⋯ These data demonstrate that tiotropium is a safe and effective once-daily anticholinergic bronchodilator and should prove useful as first-line maintenance therapy in COPD.