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Randomized Controlled Trial Multicenter Study Clinical Trial
Zafirlukast treatment for acute asthma: evaluation in a randomized, double-blind, multicenter trial.
Acute asthma causes nearly 2 million hospital emergency department (ED) visits in the United States annually, and hospitalization after an ED visit and relapse after ED discharge are common. ⋯ When added to standardized care, therapy with Z20 bid reduced the risk of relapse compared with placebo over a 28-day treatment period. One dose of Z160 in the ED also reduced the rate of extended care.