Chest
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Randomized Controlled Trial Multicenter Study
Effect of Isoniazid Therapy for Latent Tuberculosis Infection on QuantiFERON-TB Gold In-tube Responses in Tuberculin Skin Test Positive Adults in a High Tuberculosis Incidence Area: A Controlled Study.
T-cell interferon-γ release assays (IGRAs) are used in the diagnosis of Mycobacterium tuberculosis infection and could be useful biomarkers of response to treatment of latent TB infection for clinical trials, infection control units, and TB programs. ⋯ IPT had no effect on changes in QFT-GIT readouts during short-term follow-up of adults with positive tuberculin skin tests in a high TB incidence setting. QFT-GIT is unlikely to be a useful biomarker of response to treatment of latent TB infection.
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OSA & COPD PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Several studies have suggested that Sleep apnea Syndrome is frequent in the elderly. In Spain, Apnea hypopnea syndrome during sleep affects 2-6% of the middle-aged population and 15-20% of individual between 70 and 100 years of age, representing millions of people in our country. Because this disease is so prevalent, it is essential to study the differential characteristics of SAHS in the elderly. Objective: Analyse the differential characteristics of sleep apnea syndrome in older patients. ⋯ The following authors have nothing to disclose: Paola Arrieta Narvaez, Eva Mañas Baena, Rosa Mirambeaux Villalona, Carolina Gotera, Carolina Jurkojc Mohremberger, Deisy Barrios Barreto, Patricia Lazo Meneses, Patricia Castro Acosta, Maria Galarza Jimenez, Maria Salazar, Sagrario Mayoralas Alises, Salvador Diaz Lobato, Esteban Perez Rodriguez, Jonathan Cámara FernándezNo Product/Research Disclosure Information.
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Physical activity is an important clinical marker of disease status in COPD. COPD is also characterized by low-grade systemic inflammation. However, the relationship between physical activity and systemic inflammation in COPD is unclear. ⋯ People with COPD who walked the most had the lowest plasma CRP and IL-6 levels. These results provide the conceptual basis to study whether an intervention to promote walking will reduce systemic inflammation in people with COPD.
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Tuberculosis PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Romania still has the greatest number of tuberculosis cases from the EU countries. During 2002-2012, the incidence of tuberculosis in Romania decreased by 44% from 142.2 %000 to 79 %000. Even under these conditions, we retain the position of EU leaders in the number of TB cases. TB mortality has also decreased in this period. This study want to evaluate the incidence of tuberculosis in Romania since 2008-2012. ⋯ The following authors have nothing to disclose: Constantin Marica, Didilescu Cristian, Mihaela Tanasescu, Beatrice Mahler, Gina Ana CiolanNo Product/Research Disclosure Information.
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Respiratory Support PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Non invasive ventilation (NIV) ia a technical support in patients with acute or chronic respiratory failure. The NIV is used in patients with obesity hypoventilation syndrome (OHS) presenting with hypercapnic respiratory failure. Few studies examine the evolution and impact after starting this therapy in this patient group Objectives: To evaluate the result of non invasive ventilation started in obese patients in acute hypercapnic respiratory failure (AHRF) and its prognosis consequences. Asses the impact of long-term NIVMETHODS: Observational study with consecutive inclusion of obese patients with AHRF treated with NIV from February 2008 to June 2011. Obesity: BMI>30kg/m; AHRF: pH<7.35 and PaCO2> 45mmHg. Treatment: NIV started in general or respiratory wards and emergency department ⋯ The following authors have nothing to disclose: Concepcion Romero, Jesús Sánchez, Virginia Almadana, Ana Gómez-Bastero, Patricia Guerrero, Agustin Valido, Jose María Benítez, Teodoro MontemayorNo Product/Research Disclosure Information.