Chest
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Little is known about the prevalence, predictors, and outcomes of late vasopressor administration which evolves after admission to the ICU. ⋯ Late vasopressor administration was modestly associated with comorbidities and admission illness severity. One-year mortality was higher among those who received late vasopressor administration compared with only early vasopressor administration. Research to understand optimization of late vasopressor therapy administration may improve long-term mortality.