Chest
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Multicenter Study
HIGH DEFINITION VIDEOBRONCHOSCOPY FOR THE DIAGNOSIS OF AIRWAY INVOLVEMENT IN SARCOIDOSIS: THE ENHANCE SARCOIDOSIS MULTICENTER STUDY.
The ability of high-definition (HD) videobronchoscopy to detect airway involvement in sarcoidosis has not been evaluated previously. ⋯ In a population with a large prevalence of White Europeans, HD videobronchoscopy detected AAs in approximately one-half of patients with sarcoidosis. The diagnostic yield of EBB was higher in patients with parenchymal involvement on CT scan imaging and in those with AAs, especially if manifesting as cobblestoning and nodularity.
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Multicenter Study
Prospective Detection of Early Lung Cancer in COPD Patients in Regular Care by Electronic Nose Analysis of Exhaled Breath.
Patients with COPD are at high risk of lung cancer developing, but no validated predictive biomarkers have been reported to identify these patients. Molecular profiling of exhaled breath by electronic nose (eNose) technology may qualify for early detection of lung cancer in patients with COPD. ⋯ Exhaled breath analysis by eNose identified patients with COPD in whom lung cancer became clinically manifest within 2 years after inclusion. These results show that eNose assessment may detect early stages of lung cancer in patients with COPD.