Chest
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Asthma PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: The sensitivity of impulse oscillometry (IOS) to reflect different aspects of airway obstruction in obese men after intensive challenge has not been comprehensively appreciated. In obese subjects evaluated with spirometry we need more sensitive devices to assess exercise-related restrictive and obstructive abnormalities that hinder an exercise program for obese men who are going to be engaged in such programs. The objective was to measure airway responses following room temperature exercise challenge in healthy obese young men. ⋯ The following authors have nothing to disclose: Mustafa Moradi, Esmaeil IdaniNo Product/Research Disclosure Information.
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ILD Case Report Posters IISESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: HIGM are a set of disorders with intrinsic B-lymphocyte defects with class switching. This results in high or normal levels of IgM, but low or no production of other immunoglobulins, leading to immunodeficiency. At the same time, uncontrolled B-cell activation without class switch triggers lymphoproliferation and autoimmune phenomena. ⋯ A combination of Rituximab with immunoglobulin replacement could be a safe and effective therapy to control infection, lymphoproliferation and autoimmunity in patients with HIGM.Reference #1: Hennig C, Baumann U, Ilginus C, Horneff G, Foell J, Hansen G. Successful treatment of autoimmune and lymphoproliferative complications of patients with intrinsic B-cell immunodeficiencies with rituximab. Br J Haematol. 2010 Feb;148(3):445-8DISCLOSURE: The following authors have nothing to disclose: Rachel Jen, Bradly Biagioni, Pearce Wilcox, Bob SchellenbergNo Product/Research Disclosure Information.
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Cardiovascular CasesSESSION TYPE: Case ReportsPRESENTED ON: Saturday, March 22, 2014 at 04:15 PM - 05:15 PMINTRODUCTION: Primary cardiac tumors are extremely rare with a prevalence of 0.02% in pooled autopsy studies. Lymphomas involving the heart have a prevalence between 1% to 2% of primary cardiac tumors. Diagnosis usually requires tissue biopsy either by open surgical tissue resection or image-guided biopsy. We report a case of a patient who found to have a primary cardiac T-cell lymphoma (PCTCL) of the right atrium (RA) diagnosed by biopsy guided by intracardiac echocardiography (ICE). (1, 2)CASE PRESENTATION: A 66-year-old woman who presented with a 2 month history of progressive shortness of breath and orthopnea. Her ejection fraction decreased from 65% to 35% over a 4 year period. Coronary computed tomography angiography (CTA) revealed normal coronary arteries and a RA mass vs thrombus (Fig 1). A cardiac MRI with contrast was performed and the characteristic of the mass was suggestive of a lymphoma (Fig 2). Patient subsequently underwent percutaneous transcatheter biopsy of the RA mass using fluoroscopic and ICE guidance. Pathologic specimens demonstrated a T-cell lymphoma. ⋯ Patients with PCTCL typically remain asymptomatic until the mass leads to either obstruction of circulation, embolization, interference with valve function, decreased myocardial contractility or conduction disturbances. Histological diagnosis is made by biopsy and typically requires an open-chest procedure under general anesthesia. Transcatheter biopsy with transesophageal echocardiography guidance also requires general anesthesia. However, ICE imaging allows transcatheter biopsy of an intracardiac mass, especially of the right atrium. This can be made under direct visualization with conscious sedation, minimizing the risk for perforation. (3)CONCLUSIONS: Intracardiac mass biopsy using ICE is an attractive modality which provides precise localization of cardiac structures under conscious sedation. This case illustrates successful use of imaging to minimize risk in the assessment of a cardiac mass.Reference #1: Reynen K. Frequency of primary tumors of the heart. Am J Cardiol 1996;77:107-10.Reference #2: Lam KY, Dickens P, Chan AC. Tumors of the heart. A 20-year experience with a review of12,485 consecutive autopsies. Arch Pathol Lab Med 1993;117:1027-31.Reference #3: Kuppahally S.,Litwin S. Endomyocardial Biopsy of Right Atrial Angiosarcoma Guided by Intracardiac Echocardiography. Cardiology Research and Practice Volume 2010, Article ID 681726DISCLOSURE: The following authors have nothing to disclose: Ahmed Al-Badri, Sean Wilson, Chad Klinger, Carlos RuizNo Product/Research Disclosure Information.
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Lung Cancer ISESSION TYPE: Slide PresentationsPRESENTED ON: Saturday, March 22, 2014 at 02:15 PM - 03:45 PMPURPOSE: We have previously shown that timely restoration of airway patency with airway stenting in patients with malignant CAO provides both immediate palliation but also leads to improved survival. Radiation Therapy (RT) has also been used to improve airway patency in such cases. In this study, we analyze the additive salutary effects of combining airway stenting with RT for malignant CAO. ⋯ The following authors have nothing to disclose: Andrew Evans, Sadiq Rehmani, Hassan Sheikh Moghaddas, Jordan Sasson, Sarah Almubarak, Shahzad Razi, Adnan Al-Ayoubi, Faiz BhoraNo Product/Research Disclosure Information.
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Critical Care Posters IIISESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: We previously demonstrated in a clinically relevant murine model of sepsis, that animals with left ventricular (LV) dilation had better cardiovascular performance and increased survival. Using the same model of sepsis, we sought to determine if survivors have an early phenotype different from non-survivors with different resuscitation regiment. ⋯ The following authors have nothing to disclose: François Dépret, Fabien Picard, Sergio Zanotti-Cavazzoni, Steven HollenbergNo Product/Research Disclosure Information.