International forum of allergy & rhinology
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Int Forum Allergy Rhinol · Jan 2016
Randomized Controlled Trial Multicenter StudyMometasone furoate nasal spray in the treatment of nasal polyposis in Chinese patients: a double-blind, randomized, placebo-controlled trial.
Although mometasone furoate nasal spray (MFNS) has demonstrated efficacy in nasal polyposis (NP) in Western populations, data in Asian populations is limited. ⋯ This study demonstrated that MFNS was effective and well tolerated in this population of adult, Chinese patients with NP.
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Int Forum Allergy Rhinol · Nov 2014
Randomized Controlled Trial Comparative StudyHemostatic effect of hot saline irrigation during functional endoscopic sinus surgery: a randomized controlled trial.
The endoscopically magnified operative field in functional endoscopic sinus surgery (FESS) makes even a small amount of bleeding a potentially significant hindrance. It is thought that irrigation with hot saline during surgery may improve surgical field of view by producing a hemostatic effect. Our objective was to assess the effectiveness of hot saline irrigation (HSI) compared to room temperature saline irrigation (RTSI) in the control of intraoperative bleeding during FESS. ⋯ HSI may be beneficial in improving surgical field of view in FESS after 2 hours of operating time. A significant reduction in rate of blood loss may be attained with HSI.
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Int Forum Allergy Rhinol · Aug 2014
Randomized Controlled Trial Comparative StudyTopical cocaine vs adrenaline in endoscopic sinus surgery: a blinded randomized controlled study.
Adequate surgical field visualization is among the most important factors in preventing complications in functional endoscopic sinus surgery (FESS). The aim of this study was to assess the effect of topical cocaine vs adrenaline on surgical field visualization and intraoperative bleeding during FESS. ⋯ There is no difference in the quality of the surgical field achieved through the use of topical cocaine or adrenaline during FESS. Either of these agents can be effectively used for topical decongestion at the onset of surgery.
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Int Forum Allergy Rhinol · Jul 2014
Randomized Controlled TrialImproved quality of surgical field during endoscopic sinus surgery after clonidine premedication--a pilot study.
Inadequate surgical field visualization due to intraoperative bleeding during endoscopic sinus surgery (ESS) can cause major complications. The aim of this prospective study was to compare the effect of preoperative administration of clonidine and melatonin on the quality of the surgical field visualization and selected aspects of presurgical premedication. ⋯ Premedication with clonidine before ESS provides better quality of surgical field and more favorable hemodynamic profile as compared to melatonin.
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Int Forum Allergy Rhinol · Jun 2014
Randomized Controlled TrialImpact of intranasal sodium hyaluronate on the short-term quality of life of patients undergoing functional endoscopic sinus surgery for chronic rhinosinusitis.
Functional endoscopic sinus surgery (FESS) has become the treatment of choice for patients with medically resistant chronic rhinosinusitis (CRS) and nasal polyps. Despite the consolidated use of different treatments, the postoperative period is often very painful and uncomfortable, especially during the first month. Although evidence on the effectiveness of sodium hyaluronate (SH) on postoperative care following FESS is available, data on the quality of life (QoL) from the patients' perspective are still lacking. This study aimed to evaluate for the first time the effectiveness of nasal douche with SH in reducing patients' discomfort during the first month following FESS. ⋯ Our data indicate that SH significantly improves patients' short-term QoL following FESS in terms of both general health and specific sinonasal status.