The journal of trauma and acute care surgery
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J Trauma Acute Care Surg · Oct 2019
Randomized Controlled TrialKetamine/propofol admixture vs etomidate for intubation in the critically ill: KEEP PACE Randomized clinical trial.
Periintubation hypotension is associated with poor outcomes in the critically ill. We aimed to determine if an admixture of ketamine and propofol for emergent endotracheal intubation in critically ill patients was superior to etomidate. Primary endpoint was the change in mean arterial pressure from baseline to 5 minutes postdrug administration. ⋯ Therapeutic/Care Management, level II.