The journal of trauma and acute care surgery
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J Trauma Acute Care Surg · Jan 2014
Multicenter StudyPersistent inflammation, immunosuppression, and catabolism syndrome after severe blunt trauma.
We recently proffered that a new syndrome persistent inflammation, immunosuppression, and catabolism syndrome (PICS) has replaced late multiple-organ failure as a predominant phenotype of chronic critical illness. Our goal was to validate this by determining whether severely injured trauma patients with complicated outcomes have evidence of PICS at the genomic level. ⋯ Epidemiologic study, level III.
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J Trauma Acute Care Surg · Jan 2014
Multicenter StudyThe effect of epidural placement in patients after blunt thoracic trauma.
In studies of trauma patients with rib fractures, conclusions on the benefits derived from epidural analgesia are inconsistent. The purpose of this study was to further evaluate placement and efficacy of epidural analgesia nationwide. ⋯ Therapeutic study, level II.
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J Trauma Acute Care Surg · Dec 2013
Multicenter Study Comparative Study Clinical TrialMechanical ventilation weaning and extubation after spinal cord injury: a Western Trauma Association multicenter study.
Respiratory failure after acute spinal cord injury (SCI) is well recognized, but data defining which patients need long-term ventilator support and criteria for weaning and extubation are lacking. We hypothesized that many patients with SCI, even those with cervical SCI, can be successfully managed without long-term mechanical ventilation and its associated morbidity. ⋯ Prognostic study, level III.
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J Trauma Acute Care Surg · Dec 2013
Multicenter Study Comparative StudyBlunt cerebrovascular injury in children: underreported or underrecognized?: A multicenter ATOMAC study.
Blunt cerebrovascular injury (BCVI) has been well described in the adult trauma literature. The risk factors, proper screening, and treatment options are well known. In pediatric trauma, there has been very little research performed regarding this injury. We hypothesize that the incidence of BCVI in children is lower than the 1% reported incidence in adult studies and that many children at risk are not being screened properly. ⋯ Prognostic/epidemiologic study, level III; therapeutic study, level IV.
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J Trauma Acute Care Surg · Nov 2013
Multicenter Study Comparative StudySpinal cord injury without radiologic abnormality in children imaged with magnetic resonance imaging.
This study aimed to compare children diagnosed with cervical spinal cord injury without radiographic abnormality (SCIWORA) relative to whether there is evidence of cervical spinal cord abnormalities on magnetic resonance imaging (MRI). ⋯ Epidemiologic study, level III.