Respiratory investigation
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Respir Investig
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Respiratory investigation · Jan 2019
EditorialBaloxavir heralds a new era in influenza virus biology.
Baloxavir marboxil is an orally available prodrug of baloxavir acid. Japan was the first country to approve baloxavir marboxil as a treatment for influenza. ⋯ However, novel influenza variants exhibiting over 10-fold reductions in baloxavir susceptibility emerged in baloxavir-treated patients. Although further clinical investigation is required to explore this issue, baloxavir may revolutionize our understanding of influenza virus biology.