Stroke; a journal of cerebral circulation
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Multicenter Study Clinical Trial
Improving the predictive accuracy of recanalization on stroke outcome in patients treated with tissue plasminogen activator.
Although early recanalization is a powerful predictor of stroke outcome after thrombolysis, some stroke patients remain disabled despite tissue plasminogen activator (tPA)-induced recanalization. Therefore, we sought to investigate whether the predictive accuracy of early recanalization on stroke outcome is improved when combined with clinical and radiological information. ⋯ The combination of clinical, radiological, and hemodynamic information predicts with a high accuracy long-term stroke outcome during or shortly after intravenous tPA administration.