Stroke; a journal of cerebral circulation
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Randomized Controlled Trial Multicenter Study
Treatment of hyperglycemia in ischemic stroke (THIS): a randomized pilot trial.
Hyperglycemia may worsen brain injury during acute cerebral infarction. We tested the feasibility and tolerability of aggressive hyperglycemia correction with intravenous insulin compared with usual care during acute cerebral infarction. ⋯ The intravenous insulin protocol corrected hyperglycemia during acute cerebral infarction significantly better than usual care without major adverse events and should be investigated in a clinical efficacy trial.