Stroke; a journal of cerebral circulation
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Randomized Controlled Trial
Serial Alberta Stroke Program early CT score from baseline to 24 hours in Solitaire Flow Restoration with the Intention for Thrombectomy study: a novel surrogate end point for revascularization in acute stroke.
The Alberta Stroke Program Early CT Score (ASPECTS) on baseline imaging is an established predictor of acute ischemic stroke outcomes. We analyzed change on serial ASPECTS at baseline and 24-hour imaging in the Solitaire Flow Restoration with the Intention for Thrombectomy (SWIFT) study to determine prognostic value and to identify subgroups with extensive injury after intervention. ⋯ http://www.clinicaltrials.gov. Unique identifier: NCT01054560.
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Randomized Controlled Trial
Patient phenotypes associated with outcomes after aneurysmal subarachnoid hemorrhage: a principal component analysis.
Predictors of outcome after aneurysmal subarachnoid hemorrhage have been determined previously through hypothesis-driven methods that often exclude putative covariates and require a priori knowledge of potential confounders. Here, we apply a data-driven approach, principal component analysis, to identify baseline patient phenotypes that may predict neurological outcomes. ⋯ http://www.clinicaltrials.gov. Unique identifier: NCT00111085.
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Randomized Controlled Trial Multicenter Study
Hemicraniectomy and durotomy upon deterioration from infarction-related swelling trial: randomized pilot clinical trial.
Hemicraniectomy and Durotomy Upon Deterioration From Infarction-Related Swelling Trial (HeADDFIRST) was a randomized pilot study to obtain information necessary to design a Phase III trial to evaluate the benefit of surgical decompression for brain swelling from large supratentorial cerebral hemispheric infarction. ⋯ This trial was not registered because enrollment began before July 1, 2005.
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Randomized Controlled Trial
C-reactive protein as a prognostic marker after lacunar stroke: levels of inflammatory markers in the treatment of stroke study.
Inflammatory biomarkers predict incident and recurrent cardiac events, but their relationship to stroke prognosis is uncertain. We hypothesized that high-sensitivity C-reactive protein (hsCRP) predicts recurrent ischemic stroke after recent lacunar stroke. ⋯ http://www.clinicaltrials.gov. Unique identifier: NCT00059306.