JAMA internal medicine
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JAMA internal medicine · Feb 2019
Meta AnalysisAssociation of Corticosteroid Treatment With Outcomes in Adult Patients With Sepsis: A Systematic Review and Meta-analysis.
Although corticosteroids are widely used for adults with sepsis, both the overall benefit and potential risks remain unclear. ⋯ The findings suggest that administration of corticosteroids is associated with reduced 28-day mortality compared with placebo use or standard supportive care. More research is needed to associate personalized medicine with the corticosteroid treatment to select suitable patients who are more likely to show a benefit.