The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · Nov 2003
Randomized Controlled Trial Multicenter Study Clinical TrialFamily-based association analysis of beta2-adrenergic receptor polymorphisms in the childhood asthma management program.
Beta2-adrenergic receptor (B2AR) polymorphisms have been associated with a variety of asthma-related phenotypes, but association results have been inconsistent across different studies. ⋯ B2AR variants are associated with spirometric values and bronchodilator responsiveness, but different regions of the gene provide evidence for association with these phenotypes.