The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · May 2007
Multicenter StudyNot all farming environments protect against the development of asthma and wheeze in children.
In recent years, studies have shown a protective effect of being raised in a farm environment on the development of hay fever and atopic sensitization. Inconsistent data on the relation of farming to asthma and wheeze have raised some doubt about a true protective effect. ⋯ The development of atopic sensitization and atopic and nonatopic asthma is most likely determined by different environmental factors, possibly reflecting distinct pathomechanisms.