The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · Oct 2009
Randomized Controlled Trial Multicenter StudyEfficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacks.
Hereditary angioedema caused by C1 esterase inhibitor deficiency is a rare disorder. ⋯ C1 esterase inhibitor concentrate given intravenously at a dose of 20 U/kg is an effective and safe treatment for acute abdominal and facial attacks in patients with hereditary angioedema, with a rapid onset of relief.