The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · Nov 2009
Multicenter StudyPredictors of severe systemic anaphylactic reactions in patients with Hymenoptera venom allergy: importance of baseline serum tryptase-a study of the European Academy of Allergology and Clinical Immunology Interest Group on Insect Venom Hypersensitivity.
Severe anaphylaxis to honeybee or vespid stings is associated with a variety of risk factors, which are poorly defined. ⋯ In patients with honeybee or vespid venom allergy, baseline serum tryptase concentrations are associated with the risk for severe anaphylactic reactions. Preventive measures should include substitution of angiotensin-converting enzyme inhibitors.