Anesthesiology
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Editorial Comment
Regulatory Landscape for Clinical Decision Support Technology.
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Neuromonitoring plays an important role in the management of traumatic brain injury. Simultaneous assessment of cerebral hemodynamics, oxygenation, and metabolism allows an individualized approach to patient management in which therapeutic interventions intended to prevent or minimize secondary brain injury are guided by monitored changes in physiologic variables rather than generic thresholds. This narrative review describes various neuromonitoring techniques that can be used to guide the management of patients with traumatic brain injury and examines the latest evidence and expert consensus guidelines for neuromonitoring.
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Comparative Study
A Comparison of Red Cell Rejuvenation versus Mechanical Washing for the Prevention of Transfusion-Associated Organ Injury in Swine.
We evaluated the effects of two interventions that modify the red cell storage lesion on kidney and lung injury in experimental models of transfusion. ⋯ Reversal of the red cell storage lesion by rejuvenation reduces transfusion-associated organ injury in swine.