Anesthesiology
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Multicenter Study
Carbon Dioxide, Blood Pressure, and Perioperative Stroke: a Retrospective Case-Control Study.
The relationship between intraoperative physiology and postoperative stroke is incompletely understood. Preliminary data suggest that either hypo- or hypercapnia coupled with reduced cerebrovascular inflow (e.g., due to hypotension) can lead to ischemia. This study tested the hypothesis that the combination of intraoperative hypotension and either hypo- or hypercarbia is associated with postoperative ischemic stroke. ⋯ Intraoperative hypotension and carbon dioxide dysregulation may each independently increase postoperative stroke risk.
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Editorial Comment
Intraoperative Protective Mechanical Ventilation: Fact or Fiction?