Anesthesiology
The most recent articles from:
Anesthesiology
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Biography Historical Article
American society of Anesthesiologists Rovenstine lecture--1979: anesthesiologists as clinicians.
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To assess the change in venous admixture during breathing of 100 per cent oxygen (FIO2 1.0), shunt fraction (Qs/Qt) was calculated at a maintenance FIO2 (FIO2m:0.27--0.70) and at FIO2 1.0 in 40 studies of 34 patients with acute respiratory failure. At FIO2 1.0 Qs/Qt increased in 26 studies, but did not increase in 14 studies. ⋯ Respiratory failure was more severe in those in whom Qs/Qt decreased with oxygen, as indicated by high Qs/Qt values at FIO2m, evidence of diffuse pulmonary disease by roentgenography, and signs of adult respiratory distress syndrome. The authors conclude that changes in Qs/Qt in response to FIO2 1.0 in acute respiratory failure are related to the severity of respiratory insufficiency.