Clinical radiology
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To assess the ability of a semi-quantitative latex agglutination D-dimer test Accuclot with bedside measurements of arterial oxygen saturation, respiratory and cardiac rates to exclude pulmonary embolism (PE) on computed tomographic pulmonary angiography (CTPA). ⋯ A negative Accuclot D-dimer assay proved highly predictive for a negative CT pulmonary angiogram in suspected acute pulmonary embolus. If this D-dimer assay were included in the diagnostic algorithm of these patients a negative D-dimer would have unnecessary CTPA rendered in 36% of patients.
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In patients with the acute respiratory distress syndrome (ARDS), there is non-specific but widespread exudation of oedema and inflammatory fluid into the lungs. The clinical corollary (dyspnoea, refractory hypoxia, reduced pulmonary compliance and diffuse pulmonary infiltrates) is catastrophic and generally associated with a poor outcome. ⋯ In the present review, the radiological changes on plain radiography and computed tomography (CT) in patients with ARDS are discussed. Particular attention is directed at the appearances on CT: the relationships between CT features, histopathological changes and the inevitable alterations in pulmonary physiology are explored.