Clinical radiology
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Randomized Controlled Trial Comparative Study Clinical Trial
ECG-gated multislice spiral CT for diagnosis of acute pulmonary embolism.
The purpose of this study was to determine the feasibility of echocardiogram (ECG)-gated multi-slice CT angiography (MCTA) in patients with clinical suspicion of acute venous thromboembolism (VTE), to investigate the effect of ECG-gating on cardiac motion artefacts, and to determine the diagnostic reader agreement of ECG-gated MCTA in comparison with conventional MCTA. ⋯ ECG-gated pulmonary MCTA is feasible in patients with clinical suspicion of VTE. However, ECG-gated image acquisition did not influence the diagnostic reader agreement accuracy and inter-observer agreement of MCTA. Hence, it does not appear to be advantageous for the MCTA diagnosis of pulmonary embolism.
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Randomized Controlled Trial Clinical Trial
Paracetamol as a prophylactic analgesic for hysterosalpingography: a double blind randomized controlled trial.
To evaluate the effectiveness of paracetamol as a prophylactic analgesic for hysterosalpingography (HSG). ⋯ Paracetamol is not effective as a prophylactic analgesic for HSG. If a prophylactic analgesic is considered necessary for pain relief during HSG we recommend that a non-steroidal anti-inflammatory drug (NSAID) is used.
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Randomized Controlled Trial Clinical Trial
Simethicone coated cellulose as an oral contrast agent for ultrasound of the upper abdomen.
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Randomized Controlled Trial Clinical Trial
A double-blind randomised cross-over comparison of nabilone and metoclopramide in the control of radiation-induced nausea.
Forty patients who were suffering from radiation induced emesis were entered into a prospectively randomised double-blind cross-over study comparing nabilone with metoclopramide. Only patients who had at least five treatments remaining of their planned course of irradiation were randomised, in order to allow an adequate time to monitor the degree of symptom control and any adverse effects of the two drugs. Patient characteristics and the incidence and severity of nausea and vomiting were similar for the two groups. There was no difference in the efficacy of the two drugs but the incidence and severity of adverse reactions was significantly greater in those patients who received nabilone.