Plastic and reconstructive surgery
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Plast. Reconstr. Surg. · Jan 2000
Randomized Controlled Trial Comparative Study Clinical TrialBiobrane versus 1% silver sulfadiazine in second-degree pediatric burns.
Partial-thickness burns in children have been treated for many years by daily, painful tubbing, washing, and cleansing of the burn wound, followed by topical application of antimicrobial creams. Pain and impaired wound healing are the main problems. We hypothesized that the treatment of second-degree burns with Biobrane is superior to topical treatment. ⋯ None of the patients in either group presented with wound infection or needed skin autografting. In conclusion, the treatment of partial-thickness burns with Biobrane is superior to topical therapy with 1% silver sulfadiazine. Pain, pain medication requirements, wound healing time, and length of hospital stay are significantly reduced.